Learn how targeted NGS enables research of infection severity and risk factors, host genetics, and immune responses
With response to SARS-CoV-2 infection ranging from asymptomatic to severe inflammation and infection, factors such as host genetics, immune response, and associated mechanisms need to be taken into consideration to help inform potential treatment options, including research of vaccine safety/efficacy and clinical research trials.
In this collection of talks, researchers discuss how next-generation sequencing (NGS) enables scalable, comprehensive sample-to-answer solutions to study innate and adaptive immunity, gut microbiome, and more.
Webinar topics include:
- Immune response
- Host genetics
- Gut microbiome analysis
Topic: Immune response
What can B cell repertoire analysis tell us about response to COVID-19?
Director of GLAZgo Discovery Centre, College of Medical, Veterinary and Life Sciences, University of Glasgow
Topic: Immune response
Two distinct immunopathological profiles in autopsy lungs of COVID-19
Team lead molecular pathology, Kantonsspital Baselland
Attending Pathologist & Assistant Professor, University Hospital Zurich
Topics: Host genetics, virus sequencing
Integrated approach of virus sequencing and host genetics in a COVID-19 North Portuguese cohort
Principal Researcher & Group Leader, i3S-IPATIMUP
Topics: Immune response, immune repertoire analysis
TCR and BCR sequencing solutions: applications to clinical research projects at National Jewish Health
In this discussion, we present examples of how repertoire analysis can be used to answer different types of research questions. Summaries of different studies leveraging TCR and BCR sequencing in human disease research to better understand mechanisms involved in inflammatory diseases are presented. Methods of experimental design, sequencing, and analysis are introduced for each, with examples of figures that can be generated with the user-friendly analysis portal.
Associate Professor and Scientific Director of Genomics, National Jewish Health Center for Genes, Environment, and Health
Topic: Gut microbiome analysis
Understanding the potential impact of the gut microbiome on SARS-CoV-2 Research
Product Manager, Clinical Next-Generation Sequencing Division (CSD) at Thermo Fisher Scientific