Over the last two decades, DNA synthesis has established itself as a standard tool propelling life science research in a wide range of fields. In this session, we will highlight how DNA synthesis tools can support mRNA therapeutics development.

One key benefit of synthetic DNA is that it enables flexible sequence design independent of any naturally occurring template. Methods for optimization of expression in a target organism will be discussed, focusing on how to achieve best results in mammalian systems. The ability to design sequences also enables incorporation of additional layers of information into the DNA. To this end, a method for “molecular watermarking” will be described, which can enable tracking and tracing of a molecule throughout the application.

mRNA Therapeutics have a wide range of applications ranging from personalized approaches in cancer immunotherapy to global applications in the infectious disease landscape. Depending on the application, the needs for DNA input differ widely. The webinar addresses how Thermo Fisher Scientific can help with examples featuring Invitrogen GeneArt synthesis technologies to address a myriad of applications in the life science industry. In summary, this presentation will highlight how different synthetic biology technologies can support emerging needs in mRNA therapeutics development and commercialization.