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As more cell therapies progress through the clinical pipeline to commercial manufacturing, transitioning your process to a closed, modular workflow reduces the number of manual steps and open processes and helps standardize the production of T cell therapeutics by improving their quality and safety while reducing costs.

As part of our initiative to provide workflows that support closed cell therapy manufacturing, we are highlighting the incorporation of magnetic bead separation technology into a cell processing platform designed specifically for cell therapy applications. This app note provides you with a step-by-step guide on the procedure for T cell isolation and activation with Gibco CTS Dynabeads using the Gibco CTS Rotea counterflow centrifugation system and the Gibco CTS DynaMag Magnet.

In this app note, you’ll learn about:

• Reducing the number of manual touch points in your cell therapy manufacturing workflow by following a closed protocol
• Isolating CD3⁺ T cells with Gibco CTS Dynabeads CD3/CD28 beads using the Gibco CTS Rotea system and the Gibco CTS DynaMag Magnet
• Step by step instructions to guide you through the process of implementing this process into your workflow

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