This webinar highlights data from a three-part Application Note series, including the process performance and product quality from DynaDrive Single-Use Bioreactors (S.U.B.s). Join us with the Process Development Manager and the Product Director for DynaDrive S.U.B.s to understand the role of process robustness and vessel capability in a seamless system transfer, S.U.B. process comparability, and processes developed from XDR or HyPerforma S.U.B.s that were successfully handed down to DynaDrive S.U.B.s.

Key learnings:

• Four processes developed from XDR or HyPerforma S.U.B.s were successfully transferred to DynaDrive S.U.B.s
• Process performance and product quality from DynaDrive S.U.B.s. were comparable to those from XDR or HyPerforma S.U.B.s
• CHO‑S and CHO‑M cell lines showed enough robustness within the process to overcome the vessel change and scale up, while CHO‑DG44 process showed noticeable impacts of vessel type and volume to cell growth, metabolites, production, and product quality
• Understanding the process robustness and vessel capabilities are necessary for a seamless transfer from one system to another

Speakers:

Qingwei Luo
Manager, Process Development, Pharma Services
Thermo Fisher Scientific
Biography ›

Qingwei Luo holds a PhD in Microbiology from the University of Oklahoma, completed postdoctoral training at Washington University in St. Louis on Cell Biology and Immunology, and joined Patheon (acquired by Thermo Fisher in 2018) in 2016 as a Process Development Scientist. She has experience in both Upstream Process Development and Downstream Process Development. She leads a group on Cell Culture Process Development at different scales, from AMBR15/ABMR250, bench scale, pilot scale, to 2KL/5KL manufacture scale.

Kevin Mullen
Director of DynaDrive
Thermo Fisher Scientific
Biography ›

Kevin Mullen is the Director of the DynaDrive product line at Thermo Fisher Scientific and is based in Logan, Utah. Kevin has been with Thermo Fisher for 5 years and has been primarily focused on Single‑Use Bioreactors and Single‑Use Fermentors. Kevin has helped the Thermo Fisher Development Team enhance and better characterize the performance attributes of single‑use hardware systems. Kevin is primarily responsible for new hardware development and strives to make sure that single‑use systems are developed and maintained to meet the performance requirements of today and the future. Prior to joining Thermo Fisher, he spent 13 years as an engineer and product manager in the medical device industry. Kevin holds an M.S. degree and an MBA from Utah State University, majoring in Biological Engineering and business, respectively.