mRNA‑based products are rapidly growing in the biotherapeutics space. Important considerations need to be made to develop a process for mRNA synthesis that consistently generates high‑yield and high‑quality products. This 15-minute webinar discusses the material quality attributes and the process considerations that are required to successfully synthesize mRNA using in vitro transcription. It also covers the important factors that go into scaling‑up the production of mRNA‑based therapies.
Learning objectives:
- Recognize the importance of raw materials in mRNA production
- Understand quality attributes of mRNA raw materials
- Learn considerations for mRNA synthesis and scale‑up
Speaker:

Daniel Dixon, PhD
Field Applications Scientist
Nucleic Acid Therapeutics
Thermo Fisher Scientific
Daniel Dixon is a Field Applications Scientist in nucleic acid therapeutics, supporting customers and their processes. He earned his PhD in Microbiology and Cell Science with an Entomology focus in 2015. At Thermo Fisher Scientific, he started as a Lead Scientist in upstream process development. In that role he led client process development runs from thaw to the 200‑L bioreactor scale, followed by transfection/infection, viral harvest, and depth and sterile filtration.
For Research Use or Further Manufacturing. Not for diagnostic use or direct administration into humans or animals.