b'Fully integrated, high-throughput array processing Chromosome Analysis Suite (ChAS) software supports analysis for challenging genes View and summarize chromosomal aberrations across the genome, including copy number gain or loss, LOH, and mosaicism. Developed with input from leading experts, ChAS is designed specifically for copy number and The Applied Biosystems GeneChip System 3000 is a fullycytogenetics research analysis and reporting. Weintegrated platform for conducting your research using CytoScanwork with our customers, listen to their valuable feedback, and or OncoScan arrays.continually empower them with enhanced features to make The GeneChip System 3000 combines advanced design anddata analysis for their research simpler and more intuitive.automation to deliver high resolution scanning with minimizedKey featureshands-on time. This comprehensive system includes the Applied Biosystems GeneChip Scanner 3000 7G, Applied BiosystemsAnalyze copy number, mosaicism, and LOH segment data at different levels of resolutionGeneChip Fluidics Station 450, Applied Biosystems GeneChip Hybridization Oven 645, and a powerful computer workstationAutomatically prioritize segment data using installed with instrument control software. ACMG-inspired scoring When used with the optional Applied Biosystems GeneChipCustomize and load your own annotations and regions for focused analysisAutoLoader Carousel, the system helps provide complete walk-away freedom for scanning your arrays. The GeneChip ScannerStore, query, and display historic sample data and 3000 7G uses a solid-state laser so it needs no external laserannotations for streamlined analysispower supply or special cooling system and fits easily into aDirectly access NCBI, UCSC Genome Browser, DECIPHER, laboratory benchtop. Accurate gridding improves data integrity.ClinVar, ClinGen, Ensembl, and OMIM databases and othersHighly consistent scanner-to-scanner performance facilitatesExport user-selected data in formats like browser extensible data sharing among collaborators.data (BED), Applied Biosystems Affymetrix extensible data (AED), and variant call format (VCF) filesHighlights APIs to push and pull segment coordinates in and out of Higher-resolution scanning from 0.51 to 2.5 m pixelsChAS softwareautomatically selected by array type Automatic results file generation with zero manualOptimal image uniformity and collection efficiencyset-up requiredacross the entire scan area with proprietary Applied Biosystems Flying Objective Lens technology Export data in ClinVar format for easy uploading into ClinVarCompatible with the AutoLoader Carousel for completeAnnotation track to complete the OMIM morbidity mapwalk-away scanning of up to 48 arrays at a time Cost-effective approach enabling multiple assays on a single flexible instrument View ChAS training Compact size for better space utilization modulesNo laser drift and reduced scanner-to-scanner variabilityRequest aAutomatic adjustments of residual arc correction ChAS demoand x-linearity10'