b'SARS-CoV-2 researchExpanded portfolio of SARS-CoV-2 serological assays We are continually updating our portfolio of Invitrogen enzyme-linked immunosorbent assay (ELISA) kits to provide researchers with novel tools to study SARS-CoV-2 infection. The SARS-CoV-2 spike (S) protein plays a key role in receptor recognition and the cell membrane fusion process. The S protein is a trimeric, class I transmembrane glycoprotein with S1 and S2 subunits, and it is responsible for viral entry. The receptor binding domain (RBD) in the S1 subunit recognizes and binds to the host angiotensin-converting enzyme 2 (ACE2) receptor.The Invitrogen ELISA portfolio now includes kits to detect human ACE2 and antibodies that bind to the SARS-CoV-2 spike protein RBD, nucleocapsid (N) protein, and the physiologically relevant spike protein trimer (Figure 2).All available SARS-CoV-2 assays can now be accessed with our ELISA search tool.Figure 2. Principle of the assay for detecting antibodies against the SARS-CoV-2spike protein.Ordering informationProduct Cat. No.Human SARS-CoV-2 RBD ELISA Kit EH492RBHuman SARS-CoV N ELISA Kit EH490RBHuman ACE2 ELISA Kit EH489RBHuman SARS-CoV-2 Spike (Trimer) Ig Total ELISA Kit BMS2323Human SARS-CoV-2 Spike (Trimer) IgM ELISA Kit BMS2324Human SARS-CoV-2 Spike (Trimer) IgG ELISA Kit BMS2325Human SARS-CoV-2 Neutralizing Ab ELISA Kit BMS2326Learn more at thermofisher.com/sars-serology6 Inside the Cell//Issue No. 11Contents '