b'Conclusions and outlook ReferencesEarly cancer detection remains as one of the most pursued and1.Yang Z, Sweedler JV. Application of capillary electrophoresis for the early diagnosis of cancer. Anal Bioanal Chem. 2014;406(17):4013-4031. doi:10.1007/challenging goals in cancer medicine. Liquid biopsy is gainings00216-014-7722-ytraction as new discoveries demonstrate its advantages in2.Saxena D, Sheikh S, Kao G, et al. Rapid and ultrasensitive digital PCR (dPCR) detecting circulating tumor DNA in a noninvasive or minimallyprofiling of EGFRvIII in tumor cells and tissues. Neurooncol Adv. 2019;1(1):vdz030. doi:10.1093/noajnl/vdz030invasive manner when compared to tissue biopsy. Detection of3.Mehrotra M, Duose DY, Singh RR, et al. Versatile ion S5XL sequencer for targeted genetic mutations that are associated with cancer development,next generation sequencing of solid tumors in a clinical laboratory. PLoS One. particularly in cases with familial predisposition, is becoming2017;12(8):e0181968. Published 2017 Aug 2. doi:10.1371/journal.pone.0181968mainstream for early disease management and in some cases,4.Gress TM, Lausser L, Schirra LR, et al. Combined microRNA and mRNA microfluidic TaqMan array cards for the diagnosis of malignancy of multiple types prevention. As researchers uncover novel mutations andof pancreatico-biliary tumors in fine-needle aspiration material. Oncotarget. predictive biomarkers involved in cancer pathogenesis, sensitive2017;8(64):108223-108237. Published 2017 Nov 21. doi:10.18632/genetic analysis (PCR) and sequencing (NGS and Sangeroncotarget.226015.Chalela R, Gonzlez-Garca JG, Khilzi K, et al. EGFR and KRAS Mutations in Lung sequencing) technologies continue to power such discoveries.Parenchyma of Subjects With EGFR/KRAS Wild-Type Lung Adenocarcinoma. Pathol Oncol Res. 2021;27:598292. Published 2021 Mar 24. doi:10.3389/Thermo Fisher Scientific is committed to providing cancerpore.2021.598292researchers with reliable and time-tested genetic solutions that6.Siggillino A, Ulivi P, Pasini L, et al. Detection of EGFR Mutations in Plasma Cell-Free enable them to pursue the greatest expectations of precisionTumor DNA of TKI-Treated Advanced-NSCLC Patients by Three Methodologies: Scorpion-ARMS, PNAClamp, and Digital PCR. Diagnostics (Basel). 2020;10(12):1062. cancer medicine, ultimately providing more personalizedPublished 2020 Dec 7. doi:10.3390/diagnostics10121062treatment strategies and better patient outcomes in the future.7.Bai H, Bai S, Li X, et al. Establishment and Validation of the Detection of TERT Promoter Mutations by Human Gliomas U251 Cell Lines. Biomed Res Int. Thermo Fisher can help you achieve your most exciting cancer2021;2021:3271395. Published 2021 Jun 1. doi:10.1155/2021/32713958.Olarte I, Garca A, Ramos C, et al. Detection Of mutations in the isocitrate research goals with a full range of cancer genomics anddehydrogenase genes (IDH1/IDH2) using castPCRin patients with AML and their transcriptomics solutions. clinical impact in Mexico City. Onco Targets Ther. 2019;12:8023-8031. Published 2019 Oct 1. doi:10.2147/OTT.S219703Uncover cryptic cancer heterogeneity by qPCR, dPCR, NGS,9.Mighri N, Hamdi Y, Boujemaa M, et al. Identification of novel BRCA1 and RAD50 or CE mutations associated with breast cancer predisposition in Tunisian patients. Front Genet. 2020;11:552971. Published 2020 Nov 6. doi:10.3389/fgene.2020.552971Extract precise data from limited and challenging samples10.De Rienzo A, Yeap BY, Cibas ES, et al. Gene expression ratio test distinguishes normal such as FFPE tissue, precious solid-tumor biopsy samples, orlung from lung tumors in solid tissue and FNA biopsies. J Mol Diagn. 2014;16(2):267-liquid biopsies, by dPCR or qPCR 272. doi:10.1016/j.jmoldx.2013.11.008Obtain key insights from multiple perspectives provided by different technologiesContents 7'