b'Vitrobot Mark IV SystemThe Thermo Scientific Vitrobot Mark IV System assists inHighlights:robustly preparing grids for Cryo-EM. The instrument is fastFully automated, reproducible vitrification of aqueous and easy to use and allows the preparation of cryo-EM grids forsuspensionsvarious cryo-EM applications and sample types, such as purifiedPrecise control of critical process parametersproteins for SPA, cells for cryo-ET, and crystals for MicroED. Enclosed environmental chamberSample preparation is an important step in the cryo-EM workflow,High sample throughputand preparing good quality grids for subsequent imaging can be a daunting task. The Vitrobot Mark IV System helps the userEasy and flexible user interfaceby automating the vitrification process, while providing preciseSemiautomated grid transferbut flexible control over critical parameters. By making use of a temperature- and humidity-controlled climate chamber, the system provides a controlled environment for vitrification that prevents cooling and concentration artifacts that can be introduced with manual or open space vitrification systems. Learn more at thermofisher.com/em-sample-prepTest your protein research knowledge Question: Which of the following are cryo-EM techniques? (Select all that apply.)A. SILACB. SRMC. SPAD. SEMAnswer: COrdering informationProduct Quantity Cat. No.Sample prep reagentsVitroEase Cryo-EM Training Kit25 preparations A51363VitroEase Apoferritin Standard 5 x 20 mL A51362VitroEase Methylamine Tungstate Negative Stain 5 mL A51036VitroEase Methylamine Vanadate Negative Stain 5 mL A51037VitroEase Buffer Screening Kit 1 kit A49856InstrumentationVitrobot Mark IV System 1 system VITROBOTFor information on cryo-EM instruments, visit thermofisher.com/emlifesciences118 Cryo-EM sample preparation thermofisher.com/proteinbiology'