b'Multiple-biomarker (multiplex) quantitation platformsProtein multiplex immunoassays ProcartaPlex multiplex immunoassays Quantitate up to 80 analytes in only 25 L of serum orProcartaPlex multiplex immunoassays are bead-based assays for plasma, or 50 L of cell culture supernatant with ProcartaPlexprotein detection using Luminex xMAP technology. ProcartaPlex multiplex assays. assays are based on the principles of a sandwich ELISA, using two highly specific antibodies binding to different epitopes of one Gene expression multiplex assays protein. Invitrogen ProcartaPlex Simplex kits and panels can be Measure up to 80 RNA transcripts in a single well with Invitrogeneasily combined to create your own panels, or we can mix and QuantiGene Plex assays. validate a panel for you.Luminex instruments for target quantitation Why use Luminex technology?The Luminex xMAP technology combines advanced fluidics,Profile more biomarkers with less starting sample: quantitate up optics, and digital signal processing with fluorescently dyedto 80 analytes simultaneously with the INTELLIFLEX, FLEXMAP microspheres to enable the quantitation of multiple nucleic acid3D, or Luminex 200 instrument, and up to 50 analytes with or protein targets from a single sample. ProcartaPlex multiplexthe MAGPIX instrument. All of our ProcartaPlex assays are immunoassays are designed for measurement of proteincompatible with as little as 25 L of plasma or serum, or 50 L of expression, and QuantiGene Plex assays are available for nucleiccell culture supernatant.acid quantitation (Table 5).MultiomicsHigh-throughput immunoassays and gene expressionPerform multiomics studies using a proven technology on a analysisall from one supplier, on one instrument trusted platform. Hundreds of peer-reviewed publications have As a partner of Luminex, Thermo Fisher Scientific has beencited ProcartaPlex and QuantiGene Plex assays. You can have providing Luminex platform users with a comprehensivethe advantage of looking at both genomics and proteomics offering of instruments and multiplex reagents for over 20 years.all on one validated instrument platform. To learn more about ProcartaPlex and QuantiGene Plex assays are available in 96-wellQuantiGene assays, visit thermofisher.com/quantigene. and 384-well formats for high-throughput analysis.Table 5. Comparison of different multiplex assay platforms.Assays Analyte measured Plex level Targets available Custom designsProcartaPlex multiplex immunoassaysProteins 80 500 YesQuantiGene Plex RNA assaysRNA 80 17,000 YesImmunoassays thermofisher.com/proteinbiology 81'